Hi i welcome you in Pakistan if you are planning to live in Islamabad or in Lahore then you can adjust easily because more foreigner use to live.
about coming out from airport is simple and easy because everyone speaks English language, but any known person should there to pick you up and safely drop you to your location.
So step forward and make sure visa required documents are valid.
If you like to ask more then you may ask.
Have a wonderful day.